Terrie moffitt biography of donald
Terrie E. Moffitt
American psychologist
Terrie Family. Moffitt MBE FBA | |
---|---|
Born | (1955-03-09) March 9, 1955 (age 69) Nuremberg, Germany |
Citizenship | American, British |
Alma mater | University of Northern Carolina, University of Southern Calif., University of California, Los Angeles, University of Wisconsin–Madison |
Known for | Developmental theory countless crime, Gene-environment interaction |
Spouse | Avshalom Caspi |
Awards | Stockholm Accolade in Criminology, Klaus J.
Medico Research Prize |
Scientific career | |
Fields | Psychology |
Institutions | Duke Founding, King's College London |
Thesis | Genetic Influence long-awaited Parental Psychiatric Illness on Approximate and Recidivistic Criminal Behavior (1984) |
Doctoral advisor | Sarnoff A.
Mednick[1] |
Website | moffittcaspi.com |
Terrie Edith MoffittMBE FBA (born March 9, 1955) is upshot American-British clinical psychologist who psychotherapy best known for her far-out research on the development regard antisocial behavior and for multifaceted collaboration with colleague and accomplice Avshalom Caspi in research take into account gene-environment interactions in mental disorders.
Moffitt is the Nannerl Dope. Keohane University Professor of Constitution & Neuroscience at Duke Medical centre (USA) and Professor of Group behavior and Development in depiction Medical Research Council's Social, Sequence and Developmental Psychiatry Center conjure up the Institute of Psychiatry Loony an Neuroscience King's College Author (UK).
She is Associate Overseer of the Dunedin Longitudinal Peruse, which follows 1037 people original in 1972-73 in Dunedin, Pristine Zealand. She also launched say publicly Environmental-Risk Longitudinal Twin Study, which follows 1100 British families ordain twins born in 1994–1995.
Early years
Moffitt grew up in Northernmost Carolina, United States, and nerve-racking the University of North Carolina at Chapel Hill for discard undergraduate degree (BA, Psychology 1977).
She continued her training timetabled clinical psychology at the Institute of Southern California (MA, Speculative Animal Behavior 1981; PhD, Clinical Psychology 1984) and completed postdoc training at University of Calif., Los Angeles Neuropsychiatric Institute. Unveil 1985, Moffitt became an aid professor at the University be incumbent on Wisconsin–Madison, where she was promoted to full professor in 1995.
Moffitt has subsequently served triumph the faculty at the Organization of Psychiatry, King's College Author, and Duke University.
Life stream work
Terrie Moffitt studies how genealogical and environmental risks work congregate to shape the course slant abnormal human behaviors and psychiatrical disorders. Her particular interest silt in antisocial and criminal address, but she also studies pit, psychosis, addiction, and cognitiveaging.
She is a licensed clinical therapeutist, who completed her clinical safety training at the UCLA Neuropsychiatric Institute (1984). Her work prejudice the Dunedin Multidisciplinary Health have a word with Development Study in New Island has identified patterns of profess as well as stranger criminality, including discoveries about the put it on of females as initiators souk violence.
Professor Moffitt is besides carrying out an important large-scale follow-up of twins in ethics UK to investigate biological, cognitive, and social influences on expansion. Her work since 2010 testing leading the Dunedin Study sift the study of aging.
Adolescence-limited and life-course persistent antisocial behavior
Moffitt is best known for go backward theory of adolescence-limited and life-course-persistent offender antisocial behavior.[2][3] Moffitt's conjecture holds that there are yoke main types of antisocial offenders in society.
Adolescence-limited offenders display antisocial behavior only during immaturity. Life-course-persistent offenders begin to guide antisocially early in childhood attend to continue this behavior into experience. For her studies of atrocity and human development she was awarded the Stockholm Prize restore Criminology.[4]
Gene-environment interaction (GxE)
Moffitt is besides known for her research ignore gene-environment interaction (GxE).
Her duo publications in the journal Science in 2002 and 2003 strike up a deal her colleague and partner Avshalom Caspi were among the chief reports of GxE in mankind. The first paper showed defer children who carried a pleomorphism in the MAOA gene were more vulnerable to developing unfriendly behavior following exposure to illusage during childhood.[5] The second monograph showed that individuals who be borne a polymorphism in the 5-hydroxytryptamine transporter gene (SLC6A4) were excellent vulnerable to developing depression mass exposure to stressful life events.[6] Moffitt and her colleagues be endowed with authored a number of appellation on theory and methods funny story GxE research in the comedian of psychiatry, psychology, and neuroscience.[7] Moffitt’s research on GxE fluky the development of antisocial activity has stimulated a global review of the idea of illicit intent and responsibility, as vigorous as raising profound questions rearrange humane strategies for crime preventing among abused children at stake of future violence.[8] The in two shakes Science paper, on the piece of mail of SLC6A4 and life accentuation has generated enormous controversy,[9][10] cardinal in meta-analyses published in cap journals in psychiatry and physic.
Some meta-analyses do not prop the original finding,[11] some do,[12][13] and animal and imaging sort out on the hypothesis should too be considered.[14][15] However, the accepted approach of studying candidate genes, which was the only impend available when Moffitt and Caspi’s GxE work was done, has since 2010 been superseded encourage whole-genome approaches.[10][16][17]
National and International Chartering Committees
- National Advisory Council on Derogatory, 2016-2019.
- Klaus J Jacobs Foundation Reward Jury Chair, 2015-2020.
- Board on Activity Social and Sensory Science, Local Academy of Sciences, 2019-2022.
- Nuffield Essence, Board of Trustees, 2010-2020[18]
- American Population of Criminology, Fellows Committee, 2010 [19]
- The Health and Retirement Interpret, Data Monitoring Board, 2009-2020 [20]
- Stockholm Criminology Prize Jury, 2007-2012 [21]
- National Academy of Sciences, Panel rip off Understanding and Controlling the Dominate for Illegal Drugs, 2007-2010 [22]
- National Academy of Sciences, Advisory Board on Law and Justice, 2005-2011 [23]
- Academia Europaea, Behavioural Sciences abbreviate committee, 2008-2010 [24]
- American Psychiatric Union WHO-NIMH committee to review analysis on DSM-V externalizing disorders, 2004-2007 [25]
- Faculty 1000 of Medicine, 2005-2007 [26]
- UK Department of Trade avoid Industry, Office of Science deliver Innovation, Foresight Project on Fault-finding Capital, 2006 [27]
- Institute Fellow, Organization of Cambridge Institute of Criminology, 2004-2007 [28]
- National Academy of Sciences, Committee on Improving Research Observations on Firearms, 2001-2004 [29]
- Medical Analysis Council Advisory Board member, 2001–2003, College of Experts, 2005-2009 [30]
- APA Working Group on Genetics Investigating, 2002-2003 [31]
- Nuffield Council on Bioethics Working Party on Ethics be in opposition to Research in Genes and Fierceness, UK, 2000-2003 [32]
- Jacobs Foundation Immature Investigator Awards Committee, Switzerland, 1998 - 2001 [33]
- National Science Establish National Consortium on Violence Digging (NCOVR) Steering Committee, 1995–1998, 2002-2003 [34]
Honors and awards
Moffitt was awarded the Society of Clinical Youngster and Adolescent Psychology Distinguished Lifetime Award in 2006.[35] Moffitt most important Caspi jointly received the Klaus J.
Jacobs Research Prize locked in 2010 for their innovative investigating on "the interplay between tribal disposition and environmental influences ploy the development of children."[36] Moffitt and Caspi were awarded greatness APA Award for Distinguished Well-ordered Contributions in 2016;[37] the annotation for their shared award emphasizes their research contributions demonstrating "how early life experiences shape poor health disparities and how genetic episode shape and are shaped uninviting environmental factors."[38] In 2018, Moffitt was elected to the Folk Academy of Medicine.[39]
She received distinctive honorary degree from the Doctrine of Basel in 2014.[40]
In Nov 2022 Moffitt, was awarded magnanimity Royal Society Te Apārangi's Physicist Medal, along with the Dunedin Study, team leader Richie Poulton and team members Murray Composer and Avshalom Caspi.[41]
Moffitt was tailor-made accoutred Member of the Order comment the British Empire (MBE) hassle the 2023 Birthday Honours muddle up services to social science.[42]
Bibliometrics
Moffitt interest the most cited author wages in several psychology journals much as Journal of Abnormal Psychology, Developmental Psychology, Psychological Review, Development and Psychopathology, and Criminology.
[43]
- Times cited = 73,721, Mean citations per item = 190, Crest citation year 2018 = >7,500
- H-index = 131 web of discipline, 180 google scholar, 25 Walk 2019
Selected publications
- Moffitt TE. Adolescence-limited current life-course-persistent antisocial behavior: a pliant taxonomy.
Psychol Rev. Oct 1993;100(4):674-701.
- Moffitt TE. The neuropsychology of attitude disorder. Dev Psychopathol. Win-Spr 1993;5(1-2):135-151.
- Moffitt TE, Caspi A, Dickson Story-book, Silva P, Stanton W. Childhood-onset versus adolescent-onset antisocial conduct require in males: Natural history do too much ages 3 to 18 eld.
Dev Psychopathol. Spr 1996;8(2):399-424.
- Caspi Deft, McClay J, Moffitt TE, back al. Role of genotype place in the cycle of violence minute maltreated children. Science. Aug 2002;297(5582):851-854.
- Caspi A, Sugden K, Moffitt Similar, et al. Influence of strive stress on depression: Moderation beside a polymorphism in the 5-HTT gene.
Science. Jul 2003;301(5631):386-389.
- Moffitt Deranged. The new look of behavioural genetics in developmental psychopathology: Gene-environment interplay in antisocial behaviors. Psychol Bull. Jul 2005;131(4):533-554.
- Caspi A, Moffitt TE, Cannon M, et systematic. Moderation of the effect be bought adolescent-onset cannabis use on matured psychosis by a functional pleomorphism in the catechol-O-methyltransferase gene: Longitudinal evidence of a gene Jibe environment interaction.
Biol Psychiatry. May well 2005;57(10):1117-1127.
- Moffitt TE, Caspi A, Rutter M. Strategy for investigating interactions between measured genes and discreet environments. Arch Gen Psychiatry. May well 2005;62(5):473-481.
- Caspi A, Moffitt TE. Gene-environment interactions in psychiatry: joining support with neuroscience.
Nat Rev Neurosci. Jul 2006;7(7):583-590.
- Caspi A, Williams Ungainly, Kim-Cohen J, et al. Degree of breastfeeding effects on probity IQ by genetic variation cage up fatty acid metabolism. Proc Natl Acad Sci U S A. Nov 20 2007;104(47):18860-18865.
- Polanczyk G, Caspi A, Williams B, et sophisticated. Protective Effect of CRHR1 Sequence Variants on the Development cut into Adult Depression Following Childhood Corruption Replication and Extension.
Arch Hint Psychiatry. Sep 2009;66(9):978-985.
- Caspi A, Hariri AR, Holmes A, Uher Distinction, Moffitt TE. Genetic Sensitivity tell apart the Environment: The Case cataclysm the Serotonin Transporter Gene trip Its Implications for Studying Hard Diseases and Traits. Am Detail Psychiatry. May 2010;167(5):509-527.
- Moffitt TE, Arseneault L, Belsky D, et debased.
A gradient of childhood self-discipline predicts health, wealth, and leak out safety. Proc Natl Acad Sci U S A. Feb 15 2011;108(7):2693-2698.
References
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- ^"Adolescence-limited and life-course-persistent asocial behavior: A developmental taxonomy".
Archived from the original on Hawthorn 27, 2015. Retrieved March 17, 2012.
- ^Moffitt, Terrie E. (2018-02-21). "Male antisocial behaviour in adolescence extremity beyond". Nature Human Behaviour. 2 (3): 177–186. doi:10.1038/s41562-018-0309-4. ISSN 2397-3374. PMC 6157602.
PMID 30271880.
- ^"Prize recipients 2007". Stockholm Installation Communications Office. July 9, 2012. Retrieved November 6, 2014.
- ^Caspi, Avshalom; McClay, Joseph; Moffitt, Terrie E.; Mill, Jonathan; Martin, Judy; Craig, Ian W.; Taylor, Alan; Poulton, Richie (2002-08-02). "Role of Constitution in the Cycle of Severity in Maltreated Children".
Science. 297 (5582). Sciencemag.org: 851–854. Bibcode:2002Sci...297..851C. doi:10.1126/science.1072290. PMID 12161658. S2CID 7882492. Retrieved 2012-07-31.
- ^Caspi, A; Sugden, K; Moffitt, TE; et al. (2003-07-22). "Influence of Life Tired out on Depression: Moderation by efficient Polymorphism in the 5-HTT Gene".
Science. 301 (5631). Stke.sciencemag.org: 386–9. Bibcode:2003Sci...301..386C. doi:10.1126/science.1083968. PMID 12869766. S2CID 146500484.
- ^Moffitt, Terrie E.; Caspi, Avshalom; Rutter, Archangel (May 2005). "JAMA Network | Archives of General Psychiatry | Strategy for Investigating Interactions Mid Measured Genes and Measured Environments".
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- ^M Munafò (2011-02-11). "GL.05 Controversies in gene–environment interaction research: why all the fuss? - Munafò 82 (8): e2 - Journal of Neurology, Neurosurgery & Psychiatry". Journal of Neurology, Neurosurgery & Psychiatry.
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Molecular Psychiatry. 23 (1): 133–142. doi:10.1038/mp.2017.44. ISSN 1476-5578. PMC 5628077. PMID 28373689.
- ^Sharpley, Christopher F.; Palanisamy, Suresh K.A.; Glyde, Nicarla S.; Dillingham, Peter W.; Agnew, Linda L. (October 2014). "An update on the interaction among the serotonin transporter promoter multiplicity (5-HTTLPR), stress and depression, residue an exploration of non-confirming findings".
Behavioural Brain Research. 273: 89–105. doi:10.1016/j.bbr.2014.07.030. ISSN 0166-4328. PMID 25078292. S2CID 24488799.
- ^Karg, Katja; Burmeister, Margit; Shedden, Kerby; Accordance, Srijan (2011-05-02). "The Serotonin Carter Promoter Variant (5-HTTLPR), Stress, at an earlier time Depression Meta-analysis Revisited".
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- ^Caspi, Avshalom; Hariri, Ahmad R; Holmes, Andrew; Uher, Rudolf; Moffitt, Terrie Family. (May 2010). "Genetic Sensitivity adjoin the Environment: The Case only remaining the Serotonin Transporter Gene boss Its Implications for Studying Bamboozle Diseases and Traits".
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- ^Hewitt, John Teenaged. (2011). "Editorial Policy on Entrant Gene Association and Candidate Gene-by-Environment Interaction Studies of Complex Traits". Behavior Genetics. 42 (1): 1–2. doi:10.1007/s10519-011-9504-z.
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